
Science of Smiles: Evidence-Based Dentistry in Pasadena
A Biomimetic Dental Office in Pasadena focused on quality, compassionate dental care rooted in science.
View servicesWelcome to Science of Smiles, where science and compassion come together to create lasting smiles. If you’re looking for a trusted dentist in Pasadena, our team is committed to delivering personalized care using advanced technology and a gentle approach. As a leading Pasadena dentist, we focus on protecting, restoring, and enhancing your oral health so you can smile with confidence for years to come.
Discover Why Patients Love Us
dave holman
★★★★★
I woke up on Christmas morning to discover I had a cracked tooth. Living in the Palm Springs area, I still haven’t found a dentist I trust, so I called my dentist of over 40 years in Pasadena—Dr. Stephanie Lee's. The voicemail said the office was closed for the holidays and wouldn’t reopen until January 7th, but for emergencies, we were instructed to call Dr. Lee directly.
I honestly didn’t expect a response, but to my surprise, Dr. Lee called me back within 15 minutes—wow. I explained the situation, and she said she would put together a crew to help. About 30 minutes later, she called again and told me she could see me the following Tuesday. I was incredibly grateful.
When I arrived on Tuesday the 30th, I was warmly greeted by Pearl, whom I’ve known for over 40 years. She was there handling administrative duties, and Jill, the dental assistant, made me feel comfortable throughout the entire visit. Of course, Dr. Lee was there as well, and I thanked all of them for coming in during the holidays—it truly meant so much.
Dr. Lee carefully assessed the situation and confirmed that I needed a crown. Using state-of-the-art equipment, she was able to prep the tooth and create a new ceramic crown efficiently and expertly. When you love what you do, it shows—and Dr. Lee certainly does.
This experience was nothing short of a Christmas miracle. I can’t thank Dr. Lee and her team enough for their professionalism, dedication, and kindness.
Response from Science of Smiles
Dave, thank you so much for your incredibly kind and heartfelt review. We are truly touched by your words and grateful for the trust you’ve placed in us over the past 40 years—it means more than we can express.
I’m so glad we were able to be there for you during such a stressful and unexpected situation, especially over the holidays. Pearl, Jill, and I were more than happy to come in and help, and your appreciation made it all the more meaningful. Knowing you felt cared for and comfortable throughout the visit is exactly what we strive for.
It was a pleasure seeing you, even under the circumstances, and I’m grateful we could get you smiling again so quickly. Thank you for taking the time to share your experience and for being such a valued part of our dental family.
Karen Hovanitz
★★★★★
Although this was my first visit to Science of Smiles, I was immediately greeted by name when I opened the door. I have worked with Dr. Stephanie P. Lee, DDS, before, and, as always, she was warm, kind, and caring. Dr. Lee is extremely knowledgeable. She takes the time to explain theories and procedures thoroughly. I trust her completely with my complicated medical history.
Response from Science of Smiles
Thank you so much for taking the time to share your experience! We're thrilled to hear that your first visit to Science of Smiles made a positive impression, and it's always a pleasure to welcome a familiar face back — especially someone who trusts Dr. Lee with such confidence.
Your kind words about Dr. Lee’s warmth, expertise, and thoroughness truly mean a lot. She takes great pride in providing thoughtful care, especially when working with patients who have complex medical histories.
We're so grateful for your trust and look forward to continuing to support your dental health with the same level of care and attention.
YoshKirb
★★★★★
I have a lot of dental anxiety and staff here is very attentive and reassuring and I felt comfortable every step of the way. The wait time was great I was seen right away, highly recommend.
Response from Science of Smiles
Thank you so much for your kind words! We're so glad we could help make your visit a comfortable one. We understand that dental anxiety is very real, and it means a lot to know our team helped you feel reassured every step of the way. Thank you for your recommendation, we look forward to seeing you again! 😊
Sonya Parra
★★★★★
I had a very positive first experience with Dr. Lee. She has a calm, caring energy and took the time to listen to me. The front office was able to get me in the same day, even though I already had an appointment scheduled for four days later. I really appreciate Dr. Lee’s conservative approach and the fact that she gently made small adjustments to help balance my bite. Her assistant was also very welcoming. I really appreciated their kindness. ❤️
Thomas Piekunka
★★★★★
Dr. Lee is absolutely fabulous. Going to the dentist is no fun, but Dr. Lee understands that and makes the experience as comfortable as possible. She explains what’s going on and what she plans to do and then does it with expertise and confidence. I feel as though I am in great hands when I see Dr. Lee and feel that my dental health is being looked after with the greatest care. I am grateful to have Dr. Lee as one of my doctors.
Response from Science of Smiles
Thank you, Thomas! I'm so glad to hear that Dr. Lee made your dental visits comfortable and informative. It's wonderful to know you feel well cared for and confident in her expertise.
Joanna Wu
★★★★★
I highly recommend going to Science of Smiles for three reasons: the place, the people and their professionalism! I’ve been a patient here for the last couple of years. It’s a convenient location, and the office is welcoming, clean and tidy. Dr. Stephanie Lee is caring, considerate and thorough. Alongside Dr. Lee, the hygienists are detailed and highly skilled in giving quality teeth cleanings. The support staff are knowledgeable and make it a seamless process with scheduling and handling insurance. Most importantly, they are always looking out for what’s best for my teeth health and receptive to feedback.
Response from Science of Smiles
Thank you so much for your thoughtful and detailed review! We truly appreciate your kind words about our office, team, and the care you’ve received over the years. Dr. Lee and the entire staff are committed to providing a welcoming environment and the highest level of dental care, so it means a lot to hear that reflected in your experience. We’re especially grateful for your trust in us to look after your oral health, and we’re always here to support you in any way we can. Looking forward to continuing to care for your smile!
vivian badashian
★★★★★
I love getting my teeth cleaned. It's the only doctor's appointment that I affirmatively look forward to, and I am so grateful to have found this office. All the wonderful ladies at the front desk, from Maricella to Pearl, and Dr. Lee are so warm and welcoming and professional. And Angel, whom I see pretty often to do my cleanings... let me just say that that man has changed my life. It's not an overstatement. He taught me how to brush my teeth correctly and floss my teeth correctly and what type of toothbrush to use and how (electric is NOT a panacea, and certainly not for your gums!)... you wouldn't think that an adult would need be retaught these things, but I did! I had been doing it incorrectly my entire life, the result being that my gums would bleed every time I got my teeth cleaned.... Not anymore! My gums have never been happier, the happiest after a visit with him. Angel is so thorough, meticulous and obsessed with getting every little plague particle off my teeth... thank you Jesus for this man! He makes my teeth literally sparkle. I leave his chair feeling like a million bucks. Do yourself a favor and book an appointment at this office. Ask for Angel... your smile deserves it.
Response from Science of Smiles
Thank you Vivian for sharing your kind words about Angel. He really does care about our patients and it shows by how thorough and meticulous he is. We appreciate how much he makes our patients' teeth sparkle. Glad to hear you leave his chair feeling like a million bucks because we do too =)
JUDY KLINE
★★★★★
Dr. Stephanie Lee and her entire team, including the hygienists and the office receptionists are AMAZING. I've been going there for a while now and often, including for regular teeth cleaning appointments, dental checkups, Invisalign, and teeth cosmetic issues. Every appointment starts and ends so easily because the entire office is friendly, approachable, helpful & pleasant. I'm convinced that Dr. Lee cares about my teeth as much as I do . . . if not more! Dr. Lee is knowledgeable, thorough, creative, and explains things in a way that I (a non-dentist) understand. She also thinks outside the box; she doesn't rush through an appointment; and she genuinely loves her job. When Dr. Lee is working on my teeth, I often feel like she is a thoughtful artist & her work is great. My smile has definitely improved under the care of Dr. Lee and her team! Many continued thanks to all of them! I highly recommend them; and my husband goes there now too and also thinks they are all awesome.
Response from Science of Smiles
Thank you Judy for making our day with your kind and thoughtful words - it really gives us meaning in what we do day in and day out. We understand going to the dentist may not be a walk in the park and your trust in us helps make everything more enjoyable. We appreciate great patients like you who just brighten up any room they enter. Stay awesome Judy :)
About
About Biomimetic Dentistry
Biomimetic Dentistry seeks to build up teeth rather than drilling them down when treating fractured, weak, and decayed teeth.
With a biomimetic approach, we work to protect the tooth more effectively for a lifetime against bacterial infection.
A Pasadena Dentist Committed to Your Dental Health
More about usAt Science of Smiles in Pasadena, we believe that dentistry should be both compassionate and science-driven. Led by Dr. Stephanie P. Lee, DDS, our state-of-the-art Pasadena dental office is equipped with modern technology—including 3D scanners, CBCT imaging, milling units for same-day crowns, lasers, and microscopes—all tools that allow us to provide precise, comfortable, and long-lasting care.
Dr. Lee and our dedicated team specialize in preventive care, Invisalign, cosmetic dentistry, and dental implants, tailoring every treatment to your individual needs. As a woman-led practice, we proudly serve Pasadena, South Pasadena, Altadena, San Marino, La Cañada, and surrounding communities with a focus on trust, comfort, and long-term oral health.
Our services
Biomimetic Dentistry: Gentle, Effective, and Lasting
Learn more about biomimetic dentistry
Biomimetic Dentistry
Strengthen & protect your natural smile

Cosmetic Dentistry
Elevate your smile

TMJ & Sleep Dentistry
Relief from jaw pain & sleep disturbances

Preventive Dentistry
Keeping your smile healthy today and tomorrow

Restorative Dentistry
Revitalize your teeth

Pediatric Dentistry
Caring for little smiles
Problems we treat
Dental Problems We Can Treat
Our Pasadena dental team provides solutions for a wide range of oral health concerns, including:
Our credentials
Dr. Lee’s education, training and professional memberships. See them all.
Insurance Welcome
We Work With Most PPO Dental Insurance Plans
Yes, you can use your insurance benefits at our office. We work with most PPO Dental Insurance Plans as an out-of-network provider. Our team handles the insurance details for you, so you can focus on your smile, not the paperwork. Contact us today for a complimentary benefits check and breakdown of your insurance benefits at our office.




Visit us in Pasadena
200 S. El Molino Ave. Ste #6, Pasadena, CA 91101
Monday – Thursday: 8AM – 5PMFriday – Sunday: Closed
Ready for a Healthier Smile? Contact Science of Smiles Today
When you’re looking for a trusted dentist in Pasadena, choose Science of Smiles—a practice where science, technology, and compassion come together for your smile. Whether you need preventive care, advanced treatments, or cosmetic enhancements, our experienced team is here to help. Contact us today at (626) 795-0221 to schedule your appointment and discover why so many patients trust us as their Pasadena dentist.
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